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Wednesday, October 3, 2012

The effect of simultaneous negative and positive defocus on eye growth and development of refractive state in marmosets.

The effect of simultaneous negative and positive defocus on eye growth and development of refractive state in marmosets.
Benavente-Perez A, Nour A, Troilo D.
SUNY College of Optometry, New York, New York.
Invest Ophthalmol Vis Sci. 2012 Sep 21;53(10):6479-87.

In this study dual focus contact lenses used on ten marmosets were shown to alter refraction and eye length in a period of 10-12 weeks.  The length of their eyes was compared to those of marmosets who wore contact lenses without prescription and others who wore contact lenses with +5 or -5.  The marmosets with the dual focus lenses had smaller eyes than the ones who wore -5 lenses, slowing down their myopia progression.

From the abstract:
"Conclusions. Imposing hyperopic and myopic defocus simultaneously using concentric contact lenses resulted in relatively smaller and less myopic eyes, despite treated eyes being exposed to a greater percentage of negative defocus. Exposing the retina to combined dioptric powers with multifocal lenses that include positive defocus might be an effective treatment to control myopia development or progression."

Link to the abstract:

http://www.ncbi.nlm.nih.gov/pubmed/22918633